Everything about toxic megacolon: Symptoms, Causes and Treatment

Collection: Diseases and the way of treatment

Toxic megacoconon is a medical emergency

Toxic Megaklon: A dangerous disease you need to know!

Toxic megaconon is a rare and serious health complication that can be caused by conditions that cause inflammation or severe infection in the colon or colon, such as inflammatory bowel disease (IBD) or salmonella infection. In toxic megaconon, the colon is swollen, weak and inefficient and is full of food and gas. The toxins caused by the accumulation of food and gas may leak into the blood and cause infection that affects the whole body. It can also lead to shock and dehydration. Symptoms may include diarrhea, swelling and abdominal pain and fever, and you need immediate medical help.

Ulcerative colitis is a common factor of toxic megaconon

Poisoned Megaklon Causes

Toxic megaconon is the inflammatory result of the colon over time, especially if not treated. Health conditions that cause inflammation or infection in the colon and can lead to toxic megaconon are:

Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease and is the most common primary cause of toxic megaconon. The disease occurs when the immune system reacts too much and causes inflammation and ulcers in the inner layer of the large intestine. Symptoms include diarrhea, blood in the stool, abdominal pain, fever, fatigue, nausea and vomiting.

Ulcerative colitis may lead to toxic megaconon when the inner layer of the colon spreads to the inner areas of the colon. This stops the function of the colon and swells. Most of the deaths caused by ulcerative colitis are due to toxic megaconon.

Crohn's disease

Crohn's disease is another type of inflammatory bowel disease. The disease involves excessive immune reaction that causes inflammation in any part of the gastrointestinal tract, from the mouth to the anus. But it often affects the small intestine and the beginning of the colon. It can cause abdominal pain, weight loss, diarrhea, blood stool, nausea, joint pain, fever and skin rash.

Crohn's disease may also cause toxic megaconon, but it occurs less than ulcerative colitis. It is more likely to occur in the early stages of Crohn's disease.

Clostridium Dipyil infection

The infection caused by Clostridium difficile (C. DIFF) is less common, but it can inflame the intestine and cause diarrhea. Other symptoms include fever, abdominal pain, vomiting and nausea.

The likelihood of C. Diff infection when taking antibiotics or one month afterwards is 2 to 5 times more. These antibiotics can eliminate the beneficial bacteria of the intestine that prevent the growth of harmful bacteria such as C. Diff. Without proper functioning of beneficial bacteria, C. Diff infection can cause serious health problems such as toxic megaconon.

Parasitic infections

The colon may be inflamed from parasitic infections such as infections caused by some creams. Most of these infections are mild and asymptomatic. But you may also have symptoms such as diarrhea, stomach pain and fever. In serious cases, especially if you are not treated or have a weakened immune system, it can lead to toxic megaconon or other serious problems.

Bacterial infections

Intestinal infections caused by bacteria such as Salmonella, Shigella and Campylobacter can inflame the intestines. These infections cause diarrhea, abdominal and stomach pain. In severe but rare cases, they may lead to toxic megaconon.

Drugs that cause toxic megaconon

Some drugs such as drugs, anti -diamond drugs, non -steroidal anti -inflammatory drugs (NSAIDS) and antidepressants can stimulate or worsen toxic megaconon. These drugs increase the risk of toxic megaconon by reducing blood flow or changing the intestinal contraction.

Severe abdominal pain of megaklon symptoms toxic

Who are exposed to toxic megaconon?

Anyone may affect it, but some conditions, especially inflammatory bowel disease, increase the risk. Also, more likely to develop in the following:

• Diabetes

• Kidney problems

• Member transplant

• Safety system problems

• HIV/AIDS

• Heart failure

• Lung disease

Symptoms of toxic megaconon

Symptoms of toxic megakolon include:

• Pain, swelling and abdominal allergies

• Nausea

• diarrhea that may be blood or not

• then

• low blood pressure

• fast heartbeat

• Mental confusion

• Feeling unhappy

The primary symptoms of toxic megaconon

Diarrhea, often severe and blood, is initially common. You may also have fever, dizziness, abdominal swelling and fast heart rate. When the colon swells, which is a classic toxic megaconon, it cannot pass the gas through the intestine. As a result, the lower abdomen may become very swollen and painful and sensitive. If you see these symptoms, see your doctor immediately. Toxic megaconon can become serious very quickly.

When should you see a doctor?

If you have any of these symptoms, immediately look for emergency medical help or see your doctor:

• Pain and severe abdominal sensitivity

• Abdominal swelling

• repeated diarrhea and blood

• then

• fast heartbeat

• Symptoms of shock such as weak or fast pulse, pupil dilation, rapid or superficial breathing and mental confusion

Recognizing the symptoms of toxic megaconon saves the patient's life

Diagnosis of toxic megaconon

If you have toxic megaconon symptoms, the doctor and health care team will examine you. They will ask about symptoms, history of health, and conditions such as inflammatory bowel disease that cause colon inflammation.

X -rays or CT scans may be captured from the intestine to see if the colon is dilated and perform blood tests to examine the infection and other possible problems.

Abdominal swelling associated with symptoms such as fever above 2 ° C, heart rate above 2, low blood cells, low blood pressure and dehydration may refer to the diagnosis of toxic megacono.

Treatment of toxic megakolon

Treatment depends on the severity of the disease, symptoms, age, general health and the cause of the disease.

• Medications for the treatment of underlying disease that lead to toxic megaconon can help. If the cause of inflammatory bowel disease, treatment often includes steroids and immune system drugs such as inflaxing or cyclosporine. If it is caused by infection, you will probably need antibiotics. For ulcerative colitis, your doctor may prescribe antibiotics to prevent or treat bacterial infection and anti -inflammatory drugs to reduce colon swelling.

• You may also be restored to the bowel, meaning that your feeding is provided through a needle or tube instead of eating. The health care team may remove the air from the colon to reduce the pressure on the inflamed and swollen colon and prevent it from rupture. You may receive fluids through the needle to prevent dehydration and low blood pressure.

• Some people need surgery. The decision on time and the need for complex surgery is complex and there may be several factors for you and the medical team. If non -surgical treatments do not improve the condition within 1 or 2 days, you will probably need surgery to remove all or part of the colon. Also, if you find that the torn intestine is dead, you have internal bleeding, the colon is dilated or your blood becomes more toxic, you will usually need surgery directly.

• Your doctor may ask you to stop taking certain medications, such as drugs, anti -cholinergics, antidepressants and anti -diamond drugs that can worsen the toxic megacono.

Toxic megakolon can lead to sepsis

Poisoned Megaklon

Until the colon is torn, the toxic megaconon survival rate with proper treatment is over 1 %. Even if it is torn, the survival rate is about 1 %. But some studies have shown that if you have a toxic megacoconon once and treats it without surgery, it is more likely to develop it.

Key points

Toxic megaconon is a serious and life -threatening complication that may occur in rare cases when the disease or infection causes colon inflammation. If you have symptoms of toxic megakolon such as severe diarrhea, abdominal pain, swelling and allergies, heart rate and rapid breathing, nausea and vomiting, see your doctor immediately. Your doctor will recommend treatments to reduce symptoms, manage underlying disease, and help improve colon.

CT scan is used to detect toxic megacono

Frequently asked questions about toxic meghaoklon

1. What stimulates toxic megaconon?

Toxic megaconon occurs when the disease causes colon inflammation. It can be stimulated by the weak immune system, any untreated disease that causes inflammation, or the use of drugs such as anti -diamond drugs, drugs, anti -corolinergics and antidepressants.

2. Can I survive from the toxic megakolon?

Yes, you can survive the toxic megaconon, even if the colon is torn. Get medical help as soon as you see worrying symptoms.

3. Is the toxic megaconon be prevented?

Yes, you can reduce the risk of toxic megaconolon by reducing the risk of infections and managing inflammatory intestinal diseases (IBD). Measures such as hand washing, observing food safety, avoiding swallowing during swimming, and quick treatment of inflammatory bowel diseases can be helpful.

4. Does the toxic megaconon always need surgery?

No, about half of cases improve with drugs and non -surgical care such as antibiotics, steroids and bowel rest. However, if the colon is torn, some of it dies or other complications occur, surgery is essential.

5. How long does it take to treat toxic megaconon?

The time of recovery depends on the severity of the disease and the response to treatment. Non -surgical treatments may reduce symptoms within a few days, but if surgery is needed, recovery may take weeks or months, especially if ilestomy is performed.

6. Can children also have toxic megaconon?

Yes, although it is rare, children can also develop toxic megaconocolon due to inflammatory bowel disease or infections. Symptoms in children may be similar to adults and require immediate care.

The last word

Toxic megaconon is a rare but dangerous complication caused by severe inflammation or infection in the colon, such as inflammatory intestinal diseases (ulcerative colitis or crocers) or infections such as Clostridium diffiles. The disease causes swelling and paralysis of the colon and causes symptoms such as blood diarrhea, abdominal pain and swelling, fever and rapid heartbeat. Treatment includes drugs such as antibiotics and steroids, bowel rest and, in severe cases, surgery. Rapid diagnosis and treatment is critical to prevent serious complications such as colon rupture, and prevention through the management of underlying diseases and hygiene can reduce the risk.

Collected:Bitote Health